A Visayan spotted deer with progressive weight loss showed diffuse thickening and nodular changes of the pleura and peritoneum. Histology revealed a highly pleomorphic, predominantly solid neoplasm, consistent with a malignant epithelioid mesothelioma. By immunohistochemistry, expression of pan-cytokeratin, cytokeratin 5/6, and vimentin was found in tumor cells. In addition, scattered expression of calretinin, desmin and α-smooth muscle actin was present within the neoplasm. Mesotheliomas should be considered as a potential differential diagnosis for proliferative processes involving the serosa in cervids.
BT - Berliner und Münchener Tierärztliche Wochenschrift CY - Hannover DA - 02/2022 DO - 10.2376/1439-0299-2021-28 LA - English N2 -A Visayan spotted deer with progressive weight loss showed diffuse thickening and nodular changes of the pleura and peritoneum. Histology revealed a highly pleomorphic, predominantly solid neoplasm, consistent with a malignant epithelioid mesothelioma. By immunohistochemistry, expression of pan-cytokeratin, cytokeratin 5/6, and vimentin was found in tumor cells. In addition, scattered expression of calretinin, desmin and α-smooth muscle actin was present within the neoplasm. Mesotheliomas should be considered as a potential differential diagnosis for proliferative processes involving the serosa in cervids.
PB - Schlütersche Fachmedien GmbH PP - Hannover PY - 2022 EP - 1–6 T1 - Malignant epithelioid mesothelioma in a Visayan spotted deer (Cervus alfredi) T2 - Berliner und Münchener Tierärztliche Wochenschrift TI - Malignant epithelioid mesothelioma in a Visayan spotted deer (Cervus alfredi) TT - Malignes epitheloides Mesotheliom bei einem Prinz-Alfred-Hirsch (Cervus alfredi) VL - 135 SN - 1439-0299 ER -