TY - JOUR
KW - Mycobacterium xenopi
KW - non-human primate
KW - ITS-sequencing
KW - MLST-pattern
AU - M Peters
AU - P Wohlsein
AU - C Osmann
AU - I Moser
AU - S Barth
AB - <p>A 15.5 year old male white-faced saki (<em>Pithecia pithecia</em>) was euthanized due to severe emaciation and an ultrasonographically suspected hepatic neoplasm. Postmortem examination revealed disseminated granulomatous inflammation affecting liver, pancreas, kidneys, heart, skin, and various lymph nodes. Mycobacteria were isolated from pulmonary lymph node and liver, identified as <em>Mycobacterium (M.) xenopi</em> a non-tuberculous mycobacterial species of human relevance especially in cases of underlying immunodeficiency. Subsequent characterization using ITS-sequencing and MLST-pattern analysis revealed that the isolate was identical with a Canadian strain of human origin indicating a high degree of conservation across countries and host species. This case represents to our knowledge the first report of a clinical <em>M.&nbsp;xenopi</em> infection in a host species not yet reported.</p>

BT - Berliner und Münchener Tierärztliche Wochenschrift
CY - Hannover
DA - 01/2022
DO - 10.2376/1439-0299-2021-24
LA - English
N2 - <p>A 15.5 year old male white-faced saki (<em>Pithecia pithecia</em>) was euthanized due to severe emaciation and an ultrasonographically suspected hepatic neoplasm. Postmortem examination revealed disseminated granulomatous inflammation affecting liver, pancreas, kidneys, heart, skin, and various lymph nodes. Mycobacteria were isolated from pulmonary lymph node and liver, identified as <em>Mycobacterium (M.) xenopi</em> a non-tuberculous mycobacterial species of human relevance especially in cases of underlying immunodeficiency. Subsequent characterization using ITS-sequencing and MLST-pattern analysis revealed that the isolate was identical with a Canadian strain of human origin indicating a high degree of conservation across countries and host species. This case represents to our knowledge the first report of a clinical <em>M.&nbsp;xenopi</em> infection in a host species not yet reported.</p>

PB - Schlütersche Fachmedien GmbH
PP - Hannover
PY - 2022
EP - 1–5
T1 - Disseminated atypical Mycobacteriosis caused by Mycobacterium xenopi in a White-Faced Saki (Pithecia pithecia)
T2 - Berliner und Münchener Tierärztliche Wochenschrift
TI - Disseminated atypical Mycobacteriosis caused by Mycobacterium xenopi in a White-Faced Saki (Pithecia pithecia)
TT - Disseminierte atypische Mykobakteriose durch Mycobacterium xenopi bei einem Weißkopfsaki (Pithecia pithecia)
VL - 135
SN - 1439-0299
ER -