TY - JOUR
KW - microbiome
KW - non-human primate
KW - marmoset
AU - I J Knorr
AU - L Benga
AU - L Peitzmann
AU - E Engelhardt
AU - W Benten
AU - C Gougoula
AU - P Petzsch
AU - K Köhrer
AU - M Sager
AB - Although the microbiome signatures in primates are more similar to humans in comparison to microbiome of mice and rats, the study of microbiome in primate models and particularly in non-human primates such as the common marmoset (Callithrix jacchus) are sparse. 
In this study, we analyse the diversity and the taxonomic composition of the gut microbiome of the 13 members of a captive colony of common marmosets located in an experimental facility by high-throughput 16S-rRNA gene sequencing.
The gut microbiome of the marmosets displayed a complex phylogenetical and taxonomical composition, though similar among the members of the colony. Bacteria of the phyla Bacteroidetes, Firmicutes, Proteobacteria, Fusobacteria and Actinobacteria dominated the baseline microbiota. At family rank Prevotellaceae and Paraprevotellaceae dominate most of the samples, whereas Bacteroidaceae and Enterobacteriaceae were more abundant in some samples. Other families such as Bifidobacteriaceae, Fusobacteriaceae, Porphyromonadaceae, Erysipelotrichaceae, Helicobacteriaceae and Clostridiaceae were recorded in smaller percentages. At genus level, the Prevotella genus was the most abundant in ten of the 13 samples, whereas Bacteroides and an Enterobacteriaceae genus were the most abundant in the remaining samples. 
These results supplement and enrich the current knowledge on marmosets gut microbiome as a model for microbiome studies.
BT - Berliner und Münchener Tierärztliche Wochenschrift
CY - Hannover
DA - 8/2020
DO - 10.2376/1439-0299-2020-9
LA - Englisch
N2 - Although the microbiome signatures in primates are more similar to humans in comparison to microbiome of mice and rats, the study of microbiome in primate models and particularly in non-human primates such as the common marmoset (Callithrix jacchus) are sparse. 
In this study, we analyse the diversity and the taxonomic composition of the gut microbiome of the 13 members of a captive colony of common marmosets located in an experimental facility by high-throughput 16S-rRNA gene sequencing.
The gut microbiome of the marmosets displayed a complex phylogenetical and taxonomical composition, though similar among the members of the colony. Bacteria of the phyla Bacteroidetes, Firmicutes, Proteobacteria, Fusobacteria and Actinobacteria dominated the baseline microbiota. At family rank Prevotellaceae and Paraprevotellaceae dominate most of the samples, whereas Bacteroidaceae and Enterobacteriaceae were more abundant in some samples. Other families such as Bifidobacteriaceae, Fusobacteriaceae, Porphyromonadaceae, Erysipelotrichaceae, Helicobacteriaceae and Clostridiaceae were recorded in smaller percentages. At genus level, the Prevotella genus was the most abundant in ten of the 13 samples, whereas Bacteroides and an Enterobacteriaceae genus were the most abundant in the remaining samples. 
These results supplement and enrich the current knowledge on marmosets gut microbiome as a model for microbiome studies.
PB - Schlütersche Verlagsgesellschaft mbH & Co. KG
PP - Hannover
PY - 2020
T1 - Characterization of gut microbiome in a captive colony of marmosets
T2 - Berliner und Münchener Tierärztliche Wochenschrift
TI - Characterization of gut microbiome in a captive colony of marmosets
TT - Charakterisierung des Darmmikrobioms in einer Zucht- kolonie von Marmosets 
VL - 133
SN - 1439-0299
ER -