TY - JOUR KW - PRRSV KW - M. hyopneumoniae KW - simultaneous vaccination KW - field study AU - T Stricker AU - C Weissenbacher-Lang AU - M Ritzmann AU - A Ladinig AB - Vaccines against M. hyopneumoniae and PRRSV are often administered at the same time. The administration of the two vaccines mixed in one syringe (simultaneous use) would save labour and increase animal welfare by reducing the number of injections. The aim of this study was to verify under field conditions, if the simultaneous administration of the two vaccines, would be comparable to the administration of the individual vaccines.1000 piglets were divided into five groups and were either non vaccinated or vaccinated against M. hyopneumoniae and/or PRRSV-EU-type. Body weight, local reactions, morbidity and mortality were measured and clinical examinations were carried out. Blood samples were analysed serologically for the presence of antibodies against PRRSV and M. hyopneumoniae by ELISA. M. hyopneumoniae-induced lung lesion scoring (with a maximum score of 55 points) was performed at the slaughterhouse.In the 1000 pigs included in this study, no clinically relevant local or systemic reactions were observed following vaccination. No significant differences in average daily weight gain (ADWG), mortality, clinical parameters or in the prevalence of pneumonia and pleuritis at the slaughterhouse were detected between the different study groups.Significant differences were observed for the serological results, with M. hyopneumoniae antibody positive pigs in the vaccinated groups being significantly higher than in the non-vaccinated groups. Regarding the severity code of the lung lesions of the affected lungs, the lung scores from the simultaneously vaccinated pigs were significantly lower (0.82) than those from non-vaccinated pigs (1.77). Due to the low infectious pressure of both PRRSV and M. hyopneumoniae on this farm, we have to conclude that efficacy of the vaccines could not adequately be tested. BT - Berliner und Münchener Tierärztliche Wochenschrift C1 - {"oldId":70781,"title":"A study to assess the compatibility of simultaneous use of Porcine Reproductive and Respiratory Syndrome Virus (EU-type) vaccine and Mycoplasma hyopneumoniae vaccine under field conditions","topline":"Berliner und M\u00fcnchener Tier\u00e4rztliche Wochenschrift","teaserText":"Vaccines against M. hyopneumoniae and PRRSV are often administered at the same time. The administration of the two vaccines mixed in one syringe (simultaneous use) would save labour and increase animal welfare by reducing the number of ...","content":"

Summary:<\/span>
Vaccines against M. hyopneumoniae and PRRSV are often administered at the same time. The administration of the two vaccines mixed in one syringe (simultaneous use) would save labour and increase animal welfare by reducing the number of injections. The aim of this study was to verify under field conditions, if the simultaneous administration of the two vaccines, would be comparable to the administration of the individual vaccines.
1000 piglets were divided into five groups and were either non vaccinated or vaccinated against M. hyopneumoniae and\/or PRRSV-EU-type. Body weight, local reactions, morbidity and mortality were measured and clinical examinations were carried out. Blood samples were analysed serologically for the presence of antibodies against PRRSV and M. hyopneumoniae by ELISA. M. hyopneumoniae-induced lung lesion scoring (with a maximum score of 55 points) was performed at the slaughterhouse.
In the 1000 pigs included in this study, no clinically relevant local or systemic reactions were observed following vaccination. No significant differences in average daily weight gain (ADWG), mortality, clinical parameters or in the prevalence of pneumonia and pleuritis at the slaughterhouse were detected between the different study groups.Significant differences were observed for the serological results, with M. hyopneumoniae antibody positive pigs in the vaccinated groups being significantly higher than in the non-vaccinated groups. Regarding the severity code of the lung lesions of the affected lungs, the lung scores from the simultaneously vaccinated pigs were significantly lower (0.82) than those from non-vaccinated pigs (1.77). Due to the low infectious pressure of both PRRSV and M. hyopneumoniae on this farm, we have to conclude that efficacy of the vaccines could not adequately be tested.

Keywords:<\/span>
PRRSV, M. hyopneumoniae, simultaneous vaccination, field study

Zusammenfassung:<\/span>
Impfstoffe gegen M. hyopneumoniae and PRRSV werden h\u00e4ufig zur selben Zeit verabreicht. Die Applikation der beiden Impfstoffe gemischt in einer Spritze (simultane Applikation) w\u00e4re eine Arbeitserleichterung, und durch die Reduzierung der Anzahl der Injektionen pro Tier auch eine Verbesserung aus Sicht des Tierschutzes. Das Ziel der Studie war es, unter Feldbedingungen zu \u00fcberpr\u00fcfen, ob die simultane Verabreichung vergleichbar ist mit der Einzelapplikation der zwei Impfstoffe.
1000 Ferkel wurden in f\u00fcnf Gruppen aufgeteilt und entweder nicht geimpft oder gegen M. hyopneumoniae und\/oder PRRSV-EU-typ geimpft. K\u00f6rpergewicht, lokale Reaktionen, Morbidit\u00e4t und Mortalit\u00e4t wurden gemessen und klinische Untersuchungen wurden durchgef\u00fchrt. Blutproben wurden serologisch mittels ELISA auf Antik\u00f6rper gegen PRRSV und M. hyopneumoniae analysiert. Lungenl\u00e4sionen wurden am Schlachthof anhand eines M. hyopneumoniae-induzierten Lungenl\u00e4sionsscores analysiert mit einem Maximumscore von 55 Punkten.
Bei den 1000 Schweinen dieser Studie wurden keine klinisch relevanten lokalen oder systemischen Reaktionen nach der Impfung beobachtet. Es wurden zwischen den f\u00fcnf Studiengruppen keine signifikanten Unterschiede bez\u00fcglich ADWG (average daily weight gain), Mortalit\u00e4t, bei den klinischen Parametern oder bei der Pr\u00e4valenz von Pneumonien und Pleuritiden bei den Schlachtlungen nachgewiesen. Signifikante Unterschiede konnten bei den serologischen Ergebnissen ermittelt werden; die Anzahl M. hyopneumoniae Antik\u00f6rper positiver Schweine war in den geimpften Gruppen signifikant h\u00f6her als in den nicht geimpften Gruppen. Bezogen auf den Schweregrad der Lungenl\u00e4sionen der betroffenen Lungen, war der Lungenscore der simultan geimpften Schweine signifikant niedriger (0.82) als der Score der nicht geimpften Tiere (1.77). Aufgrund des niedrigen Infektionsdrucks von PRRSV und M. hyopneumoniae auf dem Studienbetrieb m\u00fcssen wir feststellen, dass die Effektivit\u00e4t der getesteten Impfstoffe nicht ausreichend untersucht werden konnte

Schl\u00fcsselw\u00f6rter:<\/span>
PRRSV, M. hyopneumoniae, simultane Impfung, Feldstudie<\/p>","categories":["Tier\u00e4rztliche Wochenschrift","Abostufe BMTW","Fachartikel"],"fromDate":"Jul 7, 2013 12:00:00 AM","toDate":"Dec 31, 2050 12:00:00 AM","oldUrls":["http:\/\/vetline.de\/-prrsv-m-hyopneumoniae-simultaneous-vaccination-field-study\/150\/3130\/70781"],"doiLanguage":"englisch","doiProductFormat":"Online","doiPublisher":"Schl\u00fctersche Verlagsgesellschaft mbH & Co. KG","doiSerialWorkTitle":"Berl. M\u00fcnch. Tier\u00e4rztl. Wschr.","doiDocumentUri":"http:\/\/www.vetline.de\/-prrsv-m-hyopneumoniae-simultaneous-vaccination-field-study\/150\/3130\/70781","doiSource":"Berl. M\u00fcnch. Tier\u00e4rztl. Wschr. 126: 5-6, 189-196 (2013)","doiissn":"0005-9366","doiNr":"10.2376\/0005-9366-126-189","doiFirstPage":"189","doiLastPage":"196","doiTransmitted":true,"doiAuthor":"Stricker T M , Weissenbacher-Lang C , Ritzmann M, Ladinig A","pdf":{"path":"http:\/\/data\/bmtw_2013_05_0189.pdf","title":"bmtw_2013_05_0189.pdf","description":"A study to assess the compatibility of simultaneous use of Porcine Reproductive and Respiratory Syndrome Virus (EU-type) vaccine and Mycoplasma hyopneumoniae vaccine under field conditions

"},"authors":[{"firstName":"T","middleName":"M","lastName":"Stricker"},{"firstName":"C","middleName":"","lastName":"Weissenbacher-Lang"},{"firstName":"M","middleName":"","lastName":"Ritzmann"},{"firstName":"A","middleName":"","lastName":"Ladinig"}],"contentOptimised":"

Summary<\/strong>
Vaccines against M. hyopneumoniae and PRRSV are often administered at the same time. The administration of the two vaccines mixed in one syringe (simultaneous use) would save labour and increase animal welfare by reducing the number of injections. The aim of this study was to verify under field conditions, if the simultaneous administration of the two vaccines, would be comparable to the administration of the individual vaccines.
1000 piglets were divided into five groups and were either non vaccinated or vaccinated against M. hyopneumoniae and\/or PRRSV-EU-type. Body weight, local reactions, morbidity and mortality were measured and clinical examinations were carried out. Blood samples were analysed serologically for the presence of antibodies against PRRSV and M. hyopneumoniae by ELISA. M. hyopneumoniae-induced lung lesion scoring (with a maximum score of 55 points) was performed at the slaughterhouse.
In the 1000 pigs included in this study, no clinically relevant local or systemic reactions were observed following vaccination. No significant differences in average daily weight gain (ADWG), mortality, clinical parameters or in the prevalence of pneumonia and pleuritis at the slaughterhouse were detected between the different study groups.Significant differences were observed for the serological results, with M. hyopneumoniae antibody positive pigs in the vaccinated groups being significantly higher than in the non-vaccinated groups. Regarding the severity code of the lung lesions of the affected lungs, the lung scores from the simultaneously vaccinated pigs were significantly lower (0.82) than those from non-vaccinated pigs (1.77). Due to the low infectious pressure of both PRRSV and M. hyopneumoniae on this farm, we have to conclude that efficacy of the vaccines could not adequately be tested.

Keywords:<\/strong>
PRRSV, M. hyopneumoniae, simultaneous vaccination, field study

Zusammenfassung<\/strong>
Impfstoffe gegen M. hyopneumoniae and PRRSV werden h\u00e4ufig zur selben Zeit verabreicht. Die Applikation der beiden Impfstoffe gemischt in einer Spritze (simultane Applikation) w\u00e4re eine Arbeitserleichterung, und durch die Reduzierung der Anzahl der Injektionen pro Tier auch eine Verbesserung aus Sicht des Tierschutzes. Das Ziel der Studie war es, unter Feldbedingungen zu \u00fcberpr\u00fcfen, ob die simultane Verabreichung vergleichbar ist mit der Einzelapplikation der zwei Impfstoffe.
1000 Ferkel wurden in f\u00fcnf Gruppen aufgeteilt und entweder nicht geimpft oder gegen M. hyopneumoniae und\/oder PRRSV-EU-typ geimpft. K\u00f6rpergewicht, lokale Reaktionen, Morbidit\u00e4t und Mortalit\u00e4t wurden gemessen und klinische Untersuchungen wurden durchgef\u00fchrt. Blutproben wurden serologisch mittels ELISA auf Antik\u00f6rper gegen PRRSV und M. hyopneumoniae analysiert. Lungenl\u00e4sionen wurden am Schlachthof anhand eines M. hyopneumoniae-induzierten Lungenl\u00e4sionsscores analysiert mit einem Maximumscore von 55 Punkten.
Bei den 1000 Schweinen dieser Studie wurden keine klinisch relevanten lokalen oder systemischen Reaktionen nach der Impfung beobachtet. Es wurden zwischen den f\u00fcnf Studiengruppen keine signifikanten Unterschiede bez\u00fcglich ADWG (average daily weight gain), Mortalit\u00e4t, bei den klinischen Parametern oder bei der Pr\u00e4valenz von Pneumonien und Pleuritiden bei den Schlachtlungen nachgewiesen. Signifikante Unterschiede konnten bei den serologischen Ergebnissen ermittelt werden; die Anzahl M. hyopneumoniae Antik\u00f6rper positiver Schweine war in den geimpften Gruppen signifikant h\u00f6her als in den nicht geimpften Gruppen. Bezogen auf den Schweregrad der Lungenl\u00e4sionen der betroffenen Lungen, war der Lungenscore der simultan geimpften Schweine signifikant niedriger (0.82) als der Score der nicht geimpften Tiere (1.77). Aufgrund des niedrigen Infektionsdrucks von PRRSV und M. hyopneumoniae auf dem Studienbetrieb m\u00fcssen wir feststellen, dass die Effektivit\u00e4t der getesteten Impfstoffe nicht ausreichend untersucht werden konnte

Schl\u00fcsselw\u00f6rter:<\/strong>
PRRSV, M. hyopneumoniae, simultane Impfung, Feldstudie<\/p>","primaryLanguage":"englisch","summary":"Vaccines against M. hyopneumoniae and PRRSV are often administered at the same time. The administration of the two vaccines mixed in one syringe (simultaneous use) would save labour and increase animal welfare by reducing the number of injections. The aim of this study was to verify under field conditions, if the simultaneous administration of the two vaccines, would be comparable to the administration of the individual vaccines.
1000 piglets were divided into five groups and were either non vaccinated or vaccinated against M. hyopneumoniae and\/or PRRSV-EU-type. Body weight, local reactions, morbidity and mortality were measured and clinical examinations were carried out. Blood samples were analysed serologically for the presence of antibodies against PRRSV and M. hyopneumoniae by ELISA. M. hyopneumoniae-induced lung lesion scoring (with a maximum score of 55 points) was performed at the slaughterhouse.
In the 1000 pigs included in this study, no clinically relevant local or systemic reactions were observed following vaccination. No significant differences in average daily weight gain (ADWG), mortality, clinical parameters or in the prevalence of pneumonia and pleuritis at the slaughterhouse were detected between the different study groups.Significant differences were observed for the serological results, with M. hyopneumoniae antibody positive pigs in the vaccinated groups being significantly higher than in the non-vaccinated groups. Regarding the severity code of the lung lesions of the affected lungs, the lung scores from the simultaneously vaccinated pigs were significantly lower (0.82) than those from non-vaccinated pigs (1.77). Due to the low infectious pressure of both PRRSV and M. hyopneumoniae on this farm, we have to conclude that efficacy of the vaccines could not adequately be tested.","keywords":["PRRSV","M. hyopneumoniae","simultaneous vaccination","field study"],"zusammenfassung":"Impfstoffe gegen M. hyopneumoniae and PRRSV werden h\u00e4ufig zur selben Zeit verabreicht. Die Applikation der beiden Impfstoffe gemischt in einer Spritze (simultane Applikation) w\u00e4re eine Arbeitserleichterung, und durch die Reduzierung der Anzahl der Injektionen pro Tier auch eine Verbesserung aus Sicht des Tierschutzes. Das Ziel der Studie war es, unter Feldbedingungen zu \u00fcberpr\u00fcfen, ob die simultane Verabreichung vergleichbar ist mit der Einzelapplikation der zwei Impfstoffe.
1000 Ferkel wurden in f\u00fcnf Gruppen aufgeteilt und entweder nicht geimpft oder gegen M. hyopneumoniae und\/oder PRRSV-EU-typ geimpft. K\u00f6rpergewicht, lokale Reaktionen, Morbidit\u00e4t und Mortalit\u00e4t wurden gemessen und klinische Untersuchungen wurden durchgef\u00fchrt. Blutproben wurden serologisch mittels ELISA auf Antik\u00f6rper gegen PRRSV und M. hyopneumoniae analysiert. Lungenl\u00e4sionen wurden am Schlachthof anhand eines M. hyopneumoniae-induzierten Lungenl\u00e4sionsscores analysiert mit einem Maximumscore von 55 Punkten.
Bei den 1000 Schweinen dieser Studie wurden keine klinisch relevanten lokalen oder systemischen Reaktionen nach der Impfung beobachtet. Es wurden zwischen den f\u00fcnf Studiengruppen keine signifikanten Unterschiede bez\u00fcglich ADWG (average daily weight gain), Mortalit\u00e4t, bei den klinischen Parametern oder bei der Pr\u00e4valenz von Pneumonien und Pleuritiden bei den Schlachtlungen nachgewiesen. Signifikante Unterschiede konnten bei den serologischen Ergebnissen ermittelt werden; die Anzahl M. hyopneumoniae Antik\u00f6rper positiver Schweine war in den geimpften Gruppen signifikant h\u00f6her als in den nicht geimpften Gruppen. Bezogen auf den Schweregrad der Lungenl\u00e4sionen der betroffenen Lungen, war der Lungenscore der simultan geimpften Schweine signifikant niedriger (0.82) als der Score der nicht geimpften Tiere (1.77). Aufgrund des niedrigen Infektionsdrucks von PRRSV und M. hyopneumoniae auf dem Studienbetrieb m\u00fcssen wir feststellen, dass die Effektivit\u00e4t der getesteten Impfstoffe nicht ausreichend untersucht werden konnte","schluesselwoerter":["PRRSV","M. hyopneumoniae","simultane Impfung","Feldstudie"],"translatedTitle":"Vaccines against M. hyopneumoniae and PRRSV are often administered at the same time. The administration of the two vaccines mixed in one syringe (simultaneous use) would save labour and increase animal welfare by reducing the number of ...","abstractE":"Vaccines against M. hyopneumoniae and PRRSV are often administered at the same time. The administration of the two vaccines mixed in one syringe (simultaneous use) would save labour and increase animal welfare by reducing the number of injections. The aim of this study was to verify under field conditions, if the simultaneous administration of the two vaccines, would be comparable to the administration of the individual vaccines.1000 piglets were divided into five groups and were either non vaccinated or vaccinated against M. hyopneumoniae and\/or PRRSV-EU-type. Body weight, local reactions, morbidity and mortality were measured and clinical examinations were carried out. Blood samples were analysed serologically for the presence of antibodies against PRRSV and M. hyopneumoniae by ELISA. M. hyopneumoniae-induced lung lesion scoring (with a maximum score of 55 points) was performed at the slaughterhouse.In the 1000 pigs included in this study, no clinically relevant local or systemic reactions were observed following vaccination. No significant differences in average daily weight gain (ADWG), mortality, clinical parameters or in the prevalence of pneumonia and pleuritis at the slaughterhouse were detected between the different study groups.Significant differences were observed for the serological results, with M. hyopneumoniae antibody positive pigs in the vaccinated groups being significantly higher than in the non-vaccinated groups. Regarding the severity code of the lung lesions of the affected lungs, the lung scores from the simultaneously vaccinated pigs were significantly lower (0.82) than those from non-vaccinated pigs (1.77). Due to the low infectious pressure of both PRRSV and M. hyopneumoniae on this farm, we have to conclude that efficacy of the vaccines could not adequately be tested.","date":{"year":2013,"date":"07\/2013","accepted":"2013-07-07"},"volume":"126","openAccess":false,"journal":"Berliner und M\u00fcnchener Tier\u00e4rztliche Wochenschrift","titleImageId":944,"pages":"189-196","redirects":["-prrsv-m-hyopneumoniae-simultaneous-vaccination-field-study\/150\/3130\/70781"],"tierartCategories":[],"artikelartCategories":["Tier\u00e4rztliche Wochenschrift","Abostufe BMTW","Fachartikel"]} CY - Hannover DA - 07/2013 DO - 10.2376/0005-9366-126-189 LA - English N2 - Vaccines against M. hyopneumoniae and PRRSV are often administered at the same time. The administration of the two vaccines mixed in one syringe (simultaneous use) would save labour and increase animal welfare by reducing the number of injections. The aim of this study was to verify under field conditions, if the simultaneous administration of the two vaccines, would be comparable to the administration of the individual vaccines.1000 piglets were divided into five groups and were either non vaccinated or vaccinated against M. hyopneumoniae and/or PRRSV-EU-type. Body weight, local reactions, morbidity and mortality were measured and clinical examinations were carried out. Blood samples were analysed serologically for the presence of antibodies against PRRSV and M. hyopneumoniae by ELISA. M. hyopneumoniae-induced lung lesion scoring (with a maximum score of 55 points) was performed at the slaughterhouse.In the 1000 pigs included in this study, no clinically relevant local or systemic reactions were observed following vaccination. No significant differences in average daily weight gain (ADWG), mortality, clinical parameters or in the prevalence of pneumonia and pleuritis at the slaughterhouse were detected between the different study groups.Significant differences were observed for the serological results, with M. hyopneumoniae antibody positive pigs in the vaccinated groups being significantly higher than in the non-vaccinated groups. Regarding the severity code of the lung lesions of the affected lungs, the lung scores from the simultaneously vaccinated pigs were significantly lower (0.82) than those from non-vaccinated pigs (1.77). Due to the low infectious pressure of both PRRSV and M. hyopneumoniae on this farm, we have to conclude that efficacy of the vaccines could not adequately be tested. PB - Schlütersche Verlagsgesellschaft mbH & Co. KG PP - Hannover PY - 2013 SP - 189 EP - 196 T1 - A study to assess the compatibility of simultaneous use of Porcine Reproductive and Respiratory Syndrome Virus (EU-type) vaccine and Mycoplasma hyopneumoniae vaccine under field conditions T2 - Berliner und Münchener Tierärztliche Wochenschrift TI - A study to assess the compatibility of simultaneous use of Porcine Reproductive and Respiratory Syndrome Virus (EU-type) vaccine and Mycoplasma hyopneumoniae vaccine under field conditions TT - Vaccines against M. hyopneumoniae and PRRSV are often administered at the same time. The administration of the two vaccines mixed in one syringe (simultaneous use) would save labour and increase animal welfare by reducing the number of ... VL - 126 SN - 0005-9366 ER -