TY - JOUR KW - avian polyomavirus KW - budgerigar fledgling disease KW - feather dysplasia KW - skin pathology of viral diseases KW - birds AU - V Herder AU - A König AU - F Seehusen AU - P Wohlsein AB - A two-week-old budgerigar (Melopsittacus undulatus) of an outdoor aviary diedsuddenly and was submitted for determination the cause of illness and death.Macroscopically, the sparsely feathered animal was in a poor body condition.Histopathological examination revealed in various mesenchymal and epithelialtissues, numerous up to 15 amp;#956;m in diameter large intranuclear, amphophilic tobasophilic inclusion bodies with a clearing of the centre. Additionally, a featherdysplasia and retention hyperkeratosis of feather follicles was found. Ultrastructurally,viral particles of approximately 35 nm in diameter were detected in thefeather follicle epithelium. A PCR for Avian Polyomavirus on fresh skin sampleswas negative whereas on formalin-fixed kidney samples with a high amount ofviral inclusion bodies yielded a positive result. In addition, viral inclusion bodydiseases, like Avian Poxvirus, Psittacine Beak and Feather disease virus, AvianAdenovirus, Psittacine Herpesvirus and papillomavirus of psittacines are summarizedand compared in the present article. BT - Berliner und Münchener Tierärztliche Wochenschrift C1 - {"oldId":69831,"title":"Avian polyomavirus infection of a fledgling budgerigar (Melopsittacus undulatus) and differential diagnoses of viral inclusions in psittacine birds \u0096 case report and mini-review","teaserText":"A two-week-old budgerigar (Melopsittacus undulatus) of an outdoor aviary diedsuddenly and was submitted for determination the cause of illness and death.Macroscopically, the sparsely feathered animal was in a poor body condition.Histopathological ...","content":"

Summary<\/span>
A two-week-old budgerigar (Melopsittacus undulatus) of an outdoor aviary diedsuddenly and was submitted for determination the cause of illness and death.Macroscopically, the sparsely feathered animal was in a poor body condition.Histopathological examination revealed in various mesenchymal and epithelialtissues, numerous up to 15 amp;#956;m in diameter large intranuclear, amphophilic tobasophilic inclusion bodies with a clearing of the centre. Additionally, a featherdysplasia and retention hyperkeratosis of feather follicles was found. Ultrastructurally,viral particles of approximately 35 nm in diameter were detected in thefeather follicle epithelium. A PCR for Avian Polyomavirus on fresh skin sampleswas negative whereas on formalin-fixed kidney samples with a high amount ofviral inclusion bodies yielded a positive result. In addition, viral inclusion bodydiseases, like Avian Poxvirus, Psittacine Beak and Feather disease virus, AvianAdenovirus, Psittacine Herpesvirus and papillomavirus of psittacines are summarizedand compared in the present article.

Keywords:<\/span>
avian polyomavirus, budgerigar fledgling disease, feather dysplasia, skin pathology of viral diseases, birds


Zusammenfassung<\/span>
Ein zwei Wochen alter Wellensittich (Melopsittacus undulatus) wurde tot in derVoliere aufgefunden und zur Untersuchung auf Erkrankungs- und Todesursacheeingesandt. Makroskopisch wurden ein schlechter Ern\u00e4hrungszustand undwenige Federn festgestellt. Histopathologisch fanden sich in epithelialen undmesenchymalen Geweben zahlreiche, bis zu 15 amp;#956;m im Durchmesser gro\u00dfe, intranukle\u00e4re,amphophile bis basophile Einschlussk\u00f6rperchen mit hellem Zentrum.Des Weiteren wurde eine Dysplasie der Federn mit Retentionshyperkeratose derFederfollikel beobachtet. Elektronenmikroskopisch wurden etwa 35 nm gro\u00dfeViruspartikel im Federfollikelepithel nachgewiesen. Nachdem der NachweisAvi\u00e4rer Polyomaviren in einer nativen Hautprobe des Tieres negativ verlief, gelanges, virale DNA in formalin-fixiertem Nierengewebe, das viele Einschlussk\u00f6rperchenaufwies, nachzuweisen. Dar\u00fcber hinaus gibt dieser Artikel eine \u00dcbersicht \u00fcbervirus-induzierte Erkrankungen von Psittaciden, die Einschlussk\u00f6rperchen verursachen,wie Avi\u00e4res Pockenvirus, Psittacine Beak and Feather disease-Virus, Avi\u00e4resAdenovirus, Psittacines Herpesvirus und Papillomvirus.

Schl\u00fcsselw\u00f6rter:<\/span>
Avi\u00e4res Polyomavirus, Budgeridar fledgling disease, Federdysplasie,Hautpathologie viraler Erkrankungen, V\u00f6gel<\/p>","categories":["Tier\u00e4rztliche Wochenschrift","Abostufe BMTW","Fachartikel"],"fromDate":"May 10, 2011 12:00:00 AM","toDate":"Dec 31, 2050 12:00:00 AM","oldUrls":["http:\/\/vetline.de\/avian-polyomavirus-budgerigar-fledgling-disease-feather-dysplasia-skin-pathology-of-viral-diseases-birds\/150\/3130\/69831"],"doiLanguage":"englisch","doiProductFormat":"Online","doiPublisher":"Schl\u00fctersche Verlagsgesellschaft mbH & Co. KG","doiSerialWorkTitle":"Berl. M\u00fcnch. Tier\u00e4rztl. Wschr.","doiDocumentUri":"http:\/\/www.vetline.de\/avian-polyomavirus-budgerigar-fledgling-disease-feather-dysplasia-skin-pathology-of-viral-diseases-birds\/150\/3130\/69831","doiSource":"Berl. M\u00fcnch. Tier\u00e4rztl. Wschr. 124: 5-6, 209-216 (2011)","doiissn":"0005-9366","doiNr":"10.2376\/0005-9366-124-209","doiFirstPage":"209","doiLastPage":"216","doiTransmitted":true,"doiAuthor":"Herder V, K\u00f6nig A, Seehusen F, Wohlsein P","pdf":{"path":"http:\/\/data\/bmtw_2011_05_0209.pdf","title":"bmtw_2011_05_0209.pdf","description":"Avian polyomavirus infection of a fledgling budgerigar (Melopsittacus undulatus) and differential diagnoses of viral inclusions in psittacine birds \u0096 case report and mini-review

"},"authors":[{"firstName":"V","middleName":"","lastName":"Herder"},{"firstName":"A","middleName":"","lastName":"K\u00f6nig"},{"firstName":"F","middleName":"","lastName":"Seehusen"},{"firstName":"P","middleName":"","lastName":"Wohlsein"}],"contentOptimised":"

Summary<\/strong>
A two-week-old budgerigar (Melopsittacus undulatus) of an outdoor aviary diedsuddenly and was submitted for determination the cause of illness and death.Macroscopically, the sparsely feathered animal was in a poor body condition.Histopathological examination revealed in various mesenchymal and epithelialtissues, numerous up to 15 amp;#956;m in diameter large intranuclear, amphophilic tobasophilic inclusion bodies with a clearing of the centre. Additionally, a featherdysplasia and retention hyperkeratosis of feather follicles was found. Ultrastructurally,viral particles of approximately 35 nm in diameter were detected in thefeather follicle epithelium. A PCR for Avian Polyomavirus on fresh skin sampleswas negative whereas on formalin-fixed kidney samples with a high amount ofviral inclusion bodies yielded a positive result. In addition, viral inclusion bodydiseases, like Avian Poxvirus, Psittacine Beak and Feather disease virus, AvianAdenovirus, Psittacine Herpesvirus and papillomavirus of psittacines are summarizedand compared in the present article.

Keywords:<\/strong>
avian polyomavirus, budgerigar fledgling disease, feather dysplasia, skin pathology of viral diseases, birds


Zusammenfassung<\/strong>
Ein zwei Wochen alter Wellensittich (Melopsittacus undulatus) wurde tot in derVoliere aufgefunden und zur Untersuchung auf Erkrankungs- und Todesursacheeingesandt. Makroskopisch wurden ein schlechter Ern\u00e4hrungszustand undwenige Federn festgestellt. Histopathologisch fanden sich in epithelialen undmesenchymalen Geweben zahlreiche, bis zu 15 amp;#956;m im Durchmesser gro\u00dfe, intranukle\u00e4re,amphophile bis basophile Einschlussk\u00f6rperchen mit hellem Zentrum.Des Weiteren wurde eine Dysplasie der Federn mit Retentionshyperkeratose derFederfollikel beobachtet. Elektronenmikroskopisch wurden etwa 35 nm gro\u00dfeViruspartikel im Federfollikelepithel nachgewiesen. Nachdem der NachweisAvi\u00e4rer Polyomaviren in einer nativen Hautprobe des Tieres negativ verlief, gelanges, virale DNA in formalin-fixiertem Nierengewebe, das viele Einschlussk\u00f6rperchenaufwies, nachzuweisen. Dar\u00fcber hinaus gibt dieser Artikel eine \u00dcbersicht \u00fcbervirus-induzierte Erkrankungen von Psittaciden, die Einschlussk\u00f6rperchen verursachen,wie Avi\u00e4res Pockenvirus, Psittacine Beak and Feather disease-Virus, Avi\u00e4resAdenovirus, Psittacines Herpesvirus und Papillomvirus.

Schl\u00fcsselw\u00f6rter:<\/strong>
Avi\u00e4res Polyomavirus, Budgeridar fledgling disease, Federdysplasie,Hautpathologie viraler Erkrankungen, V\u00f6gel<\/p>","primaryLanguage":"englisch","summary":"A two-week-old budgerigar (Melopsittacus undulatus) of an outdoor aviary diedsuddenly and was submitted for determination the cause of illness and death.Macroscopically, the sparsely feathered animal was in a poor body condition.Histopathological examination revealed in various mesenchymal and epithelialtissues, numerous up to 15 amp;#956;m in diameter large intranuclear, amphophilic tobasophilic inclusion bodies with a clearing of the centre. Additionally, a featherdysplasia and retention hyperkeratosis of feather follicles was found. Ultrastructurally,viral particles of approximately 35 nm in diameter were detected in thefeather follicle epithelium. A PCR for Avian Polyomavirus on fresh skin sampleswas negative whereas on formalin-fixed kidney samples with a high amount ofviral inclusion bodies yielded a positive result. In addition, viral inclusion bodydiseases, like Avian Poxvirus, Psittacine Beak and Feather disease virus, AvianAdenovirus, Psittacine Herpesvirus and papillomavirus of psittacines are summarizedand compared in the present article.","keywords":["avian polyomavirus","budgerigar fledgling disease","feather dysplasia","skin pathology of viral diseases","birds"],"zusammenfassung":"Ein zwei Wochen alter Wellensittich (Melopsittacus undulatus) wurde tot in derVoliere aufgefunden und zur Untersuchung auf Erkrankungs- und Todesursacheeingesandt. Makroskopisch wurden ein schlechter Ern\u00e4hrungszustand undwenige Federn festgestellt. Histopathologisch fanden sich in epithelialen undmesenchymalen Geweben zahlreiche, bis zu 15 amp;#956;m im Durchmesser gro\u00dfe, intranukle\u00e4re,amphophile bis basophile Einschlussk\u00f6rperchen mit hellem Zentrum.Des Weiteren wurde eine Dysplasie der Federn mit Retentionshyperkeratose derFederfollikel beobachtet. Elektronenmikroskopisch wurden etwa 35 nm gro\u00dfeViruspartikel im Federfollikelepithel nachgewiesen. Nachdem der NachweisAvi\u00e4rer Polyomaviren in einer nativen Hautprobe des Tieres negativ verlief, gelanges, virale DNA in formalin-fixiertem Nierengewebe, das viele Einschlussk\u00f6rperchenaufwies, nachzuweisen. Dar\u00fcber hinaus gibt dieser Artikel eine \u00dcbersicht \u00fcbervirus-induzierte Erkrankungen von Psittaciden, die Einschlussk\u00f6rperchen verursachen,wie Avi\u00e4res Pockenvirus, Psittacine Beak and Feather disease-Virus, Avi\u00e4resAdenovirus, Psittacines Herpesvirus und Papillomvirus.","schluesselwoerter":["Avi\u00e4res Polyomavirus","Budgeridar fledgling disease","Federdysplasie","Hautpathologie viraler Erkrankungen","V\u00f6gel"],"translatedTitle":"A two-week-old budgerigar (Melopsittacus undulatus) of an outdoor aviary diedsuddenly and was submitted for determination the cause of illness and death.Macroscopically, the sparsely feathered animal was in a poor body condition.Histopathological ...","abstractE":"A two-week-old budgerigar (Melopsittacus undulatus) of an outdoor aviary diedsuddenly and was submitted for determination the cause of illness and death.Macroscopically, the sparsely feathered animal was in a poor body condition.Histopathological examination revealed in various mesenchymal and epithelialtissues, numerous up to 15 amp;#956;m in diameter large intranuclear, amphophilic tobasophilic inclusion bodies with a clearing of the centre. Additionally, a featherdysplasia and retention hyperkeratosis of feather follicles was found. Ultrastructurally,viral particles of approximately 35 nm in diameter were detected in thefeather follicle epithelium. A PCR for Avian Polyomavirus on fresh skin sampleswas negative whereas on formalin-fixed kidney samples with a high amount ofviral inclusion bodies yielded a positive result. In addition, viral inclusion bodydiseases, like Avian Poxvirus, Psittacine Beak and Feather disease virus, AvianAdenovirus, Psittacine Herpesvirus and papillomavirus of psittacines are summarizedand compared in the present article.","date":{"year":2011,"date":"05\/2011","accepted":"2011-05-10"},"volume":"124","openAccess":false,"journal":"Berliner und M\u00fcnchener Tier\u00e4rztliche Wochenschrift","titleImageId":944,"pages":"209-216","redirects":["avian-polyomavirus-budgerigar-fledgling-disease-feather-dysplasia-skin-pathology-of-viral-diseases-birds\/150\/3130\/69831"],"tierartCategories":[],"artikelartCategories":["Tier\u00e4rztliche Wochenschrift","Abostufe BMTW","Fachartikel"]} CY - Hannover DA - 05/2011 DO - 10.2376/0005-9366-124-209 LA - English N2 - A two-week-old budgerigar (Melopsittacus undulatus) of an outdoor aviary diedsuddenly and was submitted for determination the cause of illness and death.Macroscopically, the sparsely feathered animal was in a poor body condition.Histopathological examination revealed in various mesenchymal and epithelialtissues, numerous up to 15 amp;#956;m in diameter large intranuclear, amphophilic tobasophilic inclusion bodies with a clearing of the centre. Additionally, a featherdysplasia and retention hyperkeratosis of feather follicles was found. Ultrastructurally,viral particles of approximately 35 nm in diameter were detected in thefeather follicle epithelium. A PCR for Avian Polyomavirus on fresh skin sampleswas negative whereas on formalin-fixed kidney samples with a high amount ofviral inclusion bodies yielded a positive result. In addition, viral inclusion bodydiseases, like Avian Poxvirus, Psittacine Beak and Feather disease virus, AvianAdenovirus, Psittacine Herpesvirus and papillomavirus of psittacines are summarizedand compared in the present article. PB - Schlütersche Verlagsgesellschaft mbH & Co. KG PP - Hannover PY - 2011 SP - 209 EP - 216 T1 - Avian polyomavirus infection of a fledgling budgerigar (Melopsittacus undulatus) and differential diagnoses of viral inclusions in psittacine birds – case report and mini-review T2 - Berliner und Münchener Tierärztliche Wochenschrift TI - Avian polyomavirus infection of a fledgling budgerigar (Melopsittacus undulatus) and differential diagnoses of viral inclusions in psittacine birds – case report and mini-review TT - A two-week-old budgerigar (Melopsittacus undulatus) of an outdoor aviary diedsuddenly and was submitted for determination the cause of illness and death.Macroscopically, the sparsely feathered animal was in a poor body condition.Histopathological ... VL - 124 SN - 0005-9366 ER -