TY - JOUR KW - mycobacteriosis KW - avian tuberculosis KW - Mycobacterium avium KW - hsp65 KW - IS901 KW - antituberculosis drugs AU - D Stępień-Pyśniak AU - K Puk AU - L Guz AU - A Wawrzyniak AU - A Marek AU - U Kosikowska AB - Avian tuberculosis, one of the most important diseases affecting various species of birds, is most often caused by Mycobacterium (M.) avium. This report describes cases of M. avium subsp. avium (MAA) infection in a white-crested Holland dwarf rooster, a male and a female golden pheasant and a male peacock. We also investigated the prevalence of mycobacteria in 60 other birds and 40 alpacas. Tissue samples of necropsied birds were cultured for mycobacteria. From nonnecropsied 60 other birds and alpacas only faecal samples were collected. Clinical signs in the affected white-crested Holland cock included gradual loss of body weight and hoarse attempts at crowing during its last 3 weeks, with a dramatic loss of body condition and depression over the final week. Only slight weakening was observed in the peacock just before its death, and the golden pheasants died suddenly. Diagnosis was confirmed by microbiological, molecular and pathological results. Mycobacterium avium subsp. avium strains were isolated from the internal organs of the affected birds. Only one faecal sample from 60 other birds was culture- and PCR-positive for M. avium subsp. avium, while another one was only PCR-positive for M. chelonae. We did not isolate any Mycobacterium spp. from faecal samples of alpacas and all of them were PCR-negative. All 18 isolated M. avium strains were resistant to rifampicin, isoniazid, ethambutol, ethionamide, capreomycin and ofloxacin, and susceptible to cycloserine and streptomycin. BT - Berliner und Münchener Tierärztliche Wochenschrift C1 - {"oldId":92778,"title":"Avian mycobacteriosis caused by Mycobacterium avium subspecies avium in four ornamental birds and in vitro drug sensitivity testing of isolates","topline":"","teaserText":"Durch Mycobacterium avium subspecies avium hervorge- rufene Gefl\u00fcgeltuberkulose bei vier Zierv\u00f6geln und Untersuchungen zur In-vitro-Empfindlichkeit der Isolate gegen Medikamente","content":"

Summary<\/span>
Avian tuberculosis, one of the most important diseases affecting various species of birds, is most often caused by Mycobacterium (M.) avium. This report describes cases of M. avium subsp. avium (MAA) infection in a white-crested Holland dwarf rooster, a male and a female golden pheasant and a male peacock. We also investigated the prevalence of mycobacteria in 60 other birds and 40 alpacas. Tissue samples of necropsied birds were cultured for mycobacteria. From nonnecropsied 60 other birds and alpacas only faecal samples were collected. Clinical signs in the affected white-crested Holland cock included gradual loss of body weight and hoarse attempts at crowing during its last 3 weeks, with a dramatic loss of body condition and depression over the final week. Only slight weakening was observed in the peacock just before its death, and the golden pheasants died suddenly. Diagnosis was confirmed by microbiological, molecular and pathological results. Mycobacterium avium subsp. avium strains were isolated from the internal organs of the affected birds. Only one faecal sample from 60 other birds was culture- and PCR-positive for M. avium subsp. avium, while another one was only PCR-positive for M. chelonae. We did not isolate any Mycobacterium spp. from faecal samples of alpacas and all of them were PCR-negative. All 18 isolated M. avium strains were resistant to rifampicin, isoniazid, ethambutol, ethionamide, capreomycin and ofloxacin, and susceptible to cycloserine and streptomycin.<\/p>

Keywords<\/span>
mycobacteriosis, avian tuberculosis, Mycobacterium avium, hsp65, IS901, antituberculosis drugs<\/p>

Zusammenfassung<\/span>
Die Gefl\u00fcgeltuberkulose, eine der wichtigsten Krankheiten verschiedener Vogelarten, wird am h\u00e4ufigsten durch Mycobacterium (M.) avium verursacht. Dieser Artikel beschreibt die Infektion durch M. avium subsp. avium (MAA) bei einem Holl\u00e4ndischen Zwerg-Wei\u00dfhaubenhahn, bei einem Goldfasanhahn und einer Goldfasanhenne sowie bei einem Pfauhahn. Gewebeproben der sezierten V\u00f6gel wurden kulturell auf Mykobakterien untersucht. Zus\u00e4tzlich wurden Kotproben 60 weiterer V\u00f6gel und 40 Alpakas aus der gleichen Tierhaltung auf Mykobakterien untersucht. Bei dem betroffenen Holl\u00e4ndischen Zwerg-Wei\u00dfhaubenhahn machte sich die Krankheit innerhalb der letzten drei Wochen durch klinische Symptome wie allm\u00e4hliche Abmagerung und heiseres Kr\u00e4hen bemerkbar. In der letzten Woche waren ein dramatischer Verlust an K\u00f6rpergewicht und Teilnahmslosigkeit zu verzeichnen. Bei dem Pfau beobachtete man nur geringgradige Schw\u00e4che direkt vor dem Tod und die Goldfasanen verendeten pl\u00f6tzlich ohne vorherige Symptome. Die Diagnose wurde durch mikrobiologische, molekulare und pathologische Untersuchungen best\u00e4tigt. Mycobacterium (M.) avium subsp. avium wurde aus inneren Organen der kranken V\u00f6gel isoliert. Nur eine der Kotproben von 60 weiteren V\u00f6geln war in der Kultur und PCR positiv f\u00fcr M. avium subsp. avium, eine andere war nur PCR-positiv f\u00fcr M. chelonae. Aus den Kotproben der Alpakas wurden keine Mycobacterium spp. isoliert und alle Proben waren PCR-negativ. Alle 18 isolierten St\u00e4mme von M. avium waren gegen\u00fcber Rifampicin, Isoniazid, Ethambutol, Ethionamid sowie Capreomycin resistent und gegen Cycloserin sowie Streptomycin empfindlich.<\/p>

Schl\u00fcsselw\u00f6rter<\/span>
Mykobakteriose, Gefl\u00fcgeltuberkulose, Mycobacterium avium, hsp65, IS901, antituberkul\u00f6se Medikamente<\/p>","categories":["Tier\u00e4rztliche Wochenschrift","Abostufe BMTW","Fachartikel"],"fromDate":"Jan 18, 2016 5:43:47 PM","oldUrls":["http:\/\/vetline.de\/avian-mycobacteriosis-caused-by-mycobacterium-avium-subspecies-avium-in-four-ornamental-birds-and-in-vitro-drug-sensitivity-testing-of-isolates\/150\/3130\/92778"],"doiLanguage":"englisch","doiProductFormat":"online","doiPublisher":"Schl\u00fctersche Verlagsgesellschaft mbH & Co. KG","doiSerialWorkTitle":"Berliner und M\u00fcnchener Tier\u00e4rztliche Wochenschrift","doiDocumentUri":"http:\/\/www.vetline.de\/avian-mycobacteriosis-caused-by-mycobacterium-avium-subspecies-avium-in-four-ornamental-birds-and-in-vitro-drug-sensitivity-testing-of-isolates\/150\/3130\/92778\/","doiSource":"Berl M\u00fcnch Tier\u00e4rztl Wochenschr 129, 65\u201371 (2016) ","doiissn":"0006-9366","doiNr":"10.2376\/0006-9366-129-65","doiFirstPage":"65","doiLastPage":"71","doiTransmitted":true,"doiAuthor":"St\u0119pie\u0144-Py\u015bniak D, Puk K, Guz L, Wawrzyniak A, Marek A, Kosikowska U","pdf":{"path":"http:\/\/data\/BMW_2016_01_02_0065.pdf","title":"BMW_2016_01_02_0065.pdf","description":"Avian mycobacteriosis caused by Mycobacterium avium subspecies avium in four ornamental birds and in vitro drug sensitivity testing of isolates"},"authors":[{"firstName":"D","middleName":"","lastName":"St\u0119pie\u0144-Py\u015bniak"},{"firstName":"K","middleName":"","lastName":"Puk"},{"firstName":"L","middleName":"","lastName":"Guz"},{"firstName":"A","middleName":"","lastName":"Wawrzyniak"},{"firstName":"A","middleName":"","lastName":"Marek"},{"firstName":"U","middleName":"","lastName":"Kosikowska"}],"contentOptimised":"

Summary<\/strong>
Avian tuberculosis, one of the most important diseases affecting various species of birds, is most often caused by Mycobacterium (M.) avium. This report describes cases of M. avium subsp. avium (MAA) infection in a white-crested Holland dwarf rooster, a male and a female golden pheasant and a male peacock. We also investigated the prevalence of mycobacteria in 60 other birds and 40 alpacas. Tissue samples of necropsied birds were cultured for mycobacteria. From nonnecropsied 60 other birds and alpacas only faecal samples were collected. Clinical signs in the affected white-crested Holland cock included gradual loss of body weight and hoarse attempts at crowing during its last 3 weeks, with a dramatic loss of body condition and depression over the final week. Only slight weakening was observed in the peacock just before its death, and the golden pheasants died suddenly. Diagnosis was confirmed by microbiological, molecular and pathological results. Mycobacterium avium subsp. avium strains were isolated from the internal organs of the affected birds. Only one faecal sample from 60 other birds was culture- and PCR-positive for M. avium subsp. avium, while another one was only PCR-positive for M. chelonae. We did not isolate any Mycobacterium spp. from faecal samples of alpacas and all of them were PCR-negative. All 18 isolated M. avium strains were resistant to rifampicin, isoniazid, ethambutol, ethionamide, capreomycin and ofloxacin, and susceptible to cycloserine and streptomycin.<\/p>

Keywords:<\/strong>
mycobacteriosis, avian tuberculosis, Mycobacterium avium, hsp65, IS901, antituberculosis drugs<\/p>

Zusammenfassung<\/strong>
Die Gefl\u00fcgeltuberkulose, eine der wichtigsten Krankheiten verschiedener Vogelarten, wird am h\u00e4ufigsten durch Mycobacterium (M.) avium verursacht. Dieser Artikel beschreibt die Infektion durch M. avium subsp. avium (MAA) bei einem Holl\u00e4ndischen Zwerg-Wei\u00dfhaubenhahn, bei einem Goldfasanhahn und einer Goldfasanhenne sowie bei einem Pfauhahn. Gewebeproben der sezierten V\u00f6gel wurden kulturell auf Mykobakterien untersucht. Zus\u00e4tzlich wurden Kotproben 60 weiterer V\u00f6gel und 40 Alpakas aus der gleichen Tierhaltung auf Mykobakterien untersucht. Bei dem betroffenen Holl\u00e4ndischen Zwerg-Wei\u00dfhaubenhahn machte sich die Krankheit innerhalb der letzten drei Wochen durch klinische Symptome wie allm\u00e4hliche Abmagerung und heiseres Kr\u00e4hen bemerkbar. In der letzten Woche waren ein dramatischer Verlust an K\u00f6rpergewicht und Teilnahmslosigkeit zu verzeichnen. Bei dem Pfau beobachtete man nur geringgradige Schw\u00e4che direkt vor dem Tod und die Goldfasanen verendeten pl\u00f6tzlich ohne vorherige Symptome. Die Diagnose wurde durch mikrobiologische, molekulare und pathologische Untersuchungen best\u00e4tigt. Mycobacterium (M.) avium subsp. avium wurde aus inneren Organen der kranken V\u00f6gel isoliert. Nur eine der Kotproben von 60 weiteren V\u00f6geln war in der Kultur und PCR positiv f\u00fcr M. avium subsp. avium, eine andere war nur PCR-positiv f\u00fcr M. chelonae. Aus den Kotproben der Alpakas wurden keine Mycobacterium spp. isoliert und alle Proben waren PCR-negativ. Alle 18 isolierten St\u00e4mme von M. avium waren gegen\u00fcber Rifampicin, Isoniazid, Ethambutol, Ethionamid sowie Capreomycin resistent und gegen Cycloserin sowie Streptomycin empfindlich.<\/p>

Schl\u00fcsselw\u00f6rter:<\/strong>
Mykobakteriose, Gefl\u00fcgeltuberkulose, Mycobacterium avium, hsp65, IS901, antituberkul\u00f6se Medikamente<\/p>","primaryLanguage":"englisch","summary":"Avian tuberculosis, one of the most important diseases affecting various species of birds, is most often caused by Mycobacterium (M.) avium. This report describes cases of M. avium subsp. avium (MAA) infection in a white-crested Holland dwarf rooster, a male and a female golden pheasant and a male peacock. We also investigated the prevalence of mycobacteria in 60 other birds and 40 alpacas. Tissue samples of necropsied birds were cultured for mycobacteria. From nonnecropsied 60 other birds and alpacas only faecal samples were collected. Clinical signs in the affected white-crested Holland cock included gradual loss of body weight and hoarse attempts at crowing during its last 3 weeks, with a dramatic loss of body condition and depression over the final week. Only slight weakening was observed in the peacock just before its death, and the golden pheasants died suddenly. Diagnosis was confirmed by microbiological, molecular and pathological results. Mycobacterium avium subsp. avium strains were isolated from the internal organs of the affected birds. Only one faecal sample from 60 other birds was culture- and PCR-positive for M. avium subsp. avium, while another one was only PCR-positive for M. chelonae. We did not isolate any Mycobacterium spp. from faecal samples of alpacas and all of them were PCR-negative. All 18 isolated M. avium strains were resistant to rifampicin, isoniazid, ethambutol, ethionamide, capreomycin and ofloxacin, and susceptible to cycloserine and streptomycin.<\/p>

","keywords":["mycobacteriosis","avian tuberculosis","Mycobacterium avium","hsp65","IS901","antituberculosis drugs"],"zusammenfassung":"Die Gefl\u00fcgeltuberkulose, eine der wichtigsten Krankheiten verschiedener Vogelarten, wird am h\u00e4ufigsten durch Mycobacterium (M.) avium verursacht. Dieser Artikel beschreibt die Infektion durch M. avium subsp. avium (MAA) bei einem Holl\u00e4ndischen Zwerg-Wei\u00dfhaubenhahn, bei einem Goldfasanhahn und einer Goldfasanhenne sowie bei einem Pfauhahn. Gewebeproben der sezierten V\u00f6gel wurden kulturell auf Mykobakterien untersucht. Zus\u00e4tzlich wurden Kotproben 60 weiterer V\u00f6gel und 40 Alpakas aus der gleichen Tierhaltung auf Mykobakterien untersucht. Bei dem betroffenen Holl\u00e4ndischen Zwerg-Wei\u00dfhaubenhahn machte sich die Krankheit innerhalb der letzten drei Wochen durch klinische Symptome wie allm\u00e4hliche Abmagerung und heiseres Kr\u00e4hen bemerkbar. In der letzten Woche waren ein dramatischer Verlust an K\u00f6rpergewicht und Teilnahmslosigkeit zu verzeichnen. Bei dem Pfau beobachtete man nur geringgradige Schw\u00e4che direkt vor dem Tod und die Goldfasanen verendeten pl\u00f6tzlich ohne vorherige Symptome. Die Diagnose wurde durch mikrobiologische, molekulare und pathologische Untersuchungen best\u00e4tigt. Mycobacterium (M.) avium subsp. avium wurde aus inneren Organen der kranken V\u00f6gel isoliert. Nur eine der Kotproben von 60 weiteren V\u00f6geln war in der Kultur und PCR positiv f\u00fcr M. avium subsp. avium, eine andere war nur PCR-positiv f\u00fcr M. chelonae. Aus den Kotproben der Alpakas wurden keine Mycobacterium spp. isoliert und alle Proben waren PCR-negativ. Alle 18 isolierten St\u00e4mme von M. avium waren gegen\u00fcber Rifampicin, Isoniazid, Ethambutol, Ethionamid sowie Capreomycin resistent und gegen Cycloserin sowie Streptomycin empfindlich.<\/p>

","schluesselwoerter":["Mykobakteriose","Gefl\u00fcgeltuberkulose","Mycobacterium avium","hsp65","IS901","antituberkul\u00f6se Medikamente"],"translatedTitle":"Durch Mycobacterium avium subspecies avium hervorge- rufene Gefl\u00fcgeltuberkulose bei vier Zierv\u00f6geln und Untersuchungen zur In-vitro-Empfindlichkeit der Isolate gegen Medikamente","abstractE":"Avian tuberculosis, one of the most important diseases affecting various species of birds, is most often caused by Mycobacterium (M.) avium. This report describes cases of M. avium subsp. avium (MAA) infection in a white-crested Holland dwarf rooster, a male and a female golden pheasant and a male peacock. We also investigated the prevalence of mycobacteria in 60 other birds and 40 alpacas. Tissue samples of necropsied birds were cultured for mycobacteria. From nonnecropsied 60 other birds and alpacas only faecal samples were collected. Clinical signs in the affected white-crested Holland cock included gradual loss of body weight and hoarse attempts at crowing during its last 3 weeks, with a dramatic loss of body condition and depression over the final week. Only slight weakening was observed in the peacock just before its death, and the golden pheasants died suddenly. Diagnosis was confirmed by microbiological, molecular and pathological results. Mycobacterium avium subsp. avium strains were isolated from the internal organs of the affected birds. Only one faecal sample from 60 other birds was culture- and PCR-positive for M. avium subsp. avium, while another one was only PCR-positive for M. chelonae. We did not isolate any Mycobacterium spp. from faecal samples of alpacas and all of them were PCR-negative. All 18 isolated M. avium strains were resistant to rifampicin, isoniazid, ethambutol, ethionamide, capreomycin and ofloxacin, and susceptible to cycloserine and streptomycin.","date":{"year":2016,"date":"01\/2016","accepted":"2016-01-18"},"volume":"129","openAccess":false,"journal":"Berliner und M\u00fcnchener Tier\u00e4rztliche Wochenschrift","titleImageId":944,"pages":"65-71","redirects":["avian-mycobacteriosis-caused-by-mycobacterium-avium-subspecies-avium-in-four-ornamental-birds-and-in-vitro-drug-sensitivity-testing-of-isolates\/150\/3130\/92778"],"tierartCategories":[],"artikelartCategories":["Tier\u00e4rztliche Wochenschrift","Abostufe BMTW","Fachartikel"]} CY - Hannover DA - 01/2016 DO - 10.2376/0006-9366-129-65 ET - 1/2 LA - English N2 - Avian tuberculosis, one of the most important diseases affecting various species of birds, is most often caused by Mycobacterium (M.) avium. This report describes cases of M. avium subsp. avium (MAA) infection in a white-crested Holland dwarf rooster, a male and a female golden pheasant and a male peacock. We also investigated the prevalence of mycobacteria in 60 other birds and 40 alpacas. Tissue samples of necropsied birds were cultured for mycobacteria. From nonnecropsied 60 other birds and alpacas only faecal samples were collected. Clinical signs in the affected white-crested Holland cock included gradual loss of body weight and hoarse attempts at crowing during its last 3 weeks, with a dramatic loss of body condition and depression over the final week. Only slight weakening was observed in the peacock just before its death, and the golden pheasants died suddenly. Diagnosis was confirmed by microbiological, molecular and pathological results. Mycobacterium avium subsp. avium strains were isolated from the internal organs of the affected birds. Only one faecal sample from 60 other birds was culture- and PCR-positive for M. avium subsp. avium, while another one was only PCR-positive for M. chelonae. We did not isolate any Mycobacterium spp. from faecal samples of alpacas and all of them were PCR-negative. All 18 isolated M. avium strains were resistant to rifampicin, isoniazid, ethambutol, ethionamide, capreomycin and ofloxacin, and susceptible to cycloserine and streptomycin. PB - Schlütersche Verlagsgesellschaft mbH & Co. KG PP - Hannover PY - 2016 SP - 65 EP - 71 T1 - Avian mycobacteriosis caused by Mycobacterium avium subspecies avium in four ornamental birds and in vitro drug sensitivity testing of isolates T2 - Berliner und Münchener Tierärztliche Wochenschrift TI - Avian mycobacteriosis caused by Mycobacterium avium subspecies avium in four ornamental birds and in vitro drug sensitivity testing of isolates TT - Durch Mycobacterium avium subspecies avium hervorgerufene Geflügeltuberkulose bei vier Ziervögeln und Untersuchungen zur In-vitro-Empfindlichkeit der Isolate gegen Medikamente VL - 129 SN - 0006-9366 ER -