01246nas a2200253   4500000000100000000000100001008004100002260005300043653001700096653002500113653001100138653001000149653002500159100001200184700001400196700001200210700001400222700001400236245008200250300001000332490000800342520062800350022001400978       2022                            d  c02/2022bSchlütersche Fachmedien GmbHaHannover10amesothelioma10avisayan spotted deer10aserosa10aTumor10aimmunohistochemistry1 aM Bazin1 aJ Schwinn1 aB Kühl1 aF Armando1 aA Beineke00aMalignant epithelioid mesothelioma in a Visayan spotted deer (Cervus alfredi)  a1–60 v1353 a<p>A Visayan spotted deer with progressive weight loss showed diffuse thickening and nodular changes of the pleura and peritoneum. Histology revealed a highly pleomorphic, predominantly solid neoplasm, consistent with a malignant epithelioid mesothelioma. By immunohistochemistry, expression of pan-cytokeratin, cytokeratin 5/6, and vimentin was found in tumor cells. In addition, scattered expression of calretinin, desmin and α-smooth muscle actin was present within the neoplasm. Mesotheliomas should be considered as a potential differential diagnosis for proliferative processes involving the serosa in cervids.</p>
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