01548nas a2200241   4500000000100000000000100001008004100002260005300043653002500096653002200121653001900143653001700162100001300179700001500192700001300207700001200220700001200232245011500244300001000359490000800369520091500377022001401292       2022                            d  c01/2022bSchlütersche Fachmedien GmbHaHannover10aMycobacterium xenopi10anon-human primate10aITS-sequencing10aMLST-pattern1 aM Peters1 aP Wohlsein1 aC Osmann1 aI Moser1 aS Barth00aDisseminated atypical Mycobacteriosis caused by Mycobacterium xenopi in a White-Faced Saki (Pithecia pithecia)  a1–50 v1353 a<p>A 15.5 year old male white-faced saki (<em>Pithecia pithecia</em>) was euthanized due to severe emaciation and an ultrasonographically suspected hepatic neoplasm. Postmortem examination revealed disseminated granulomatous inflammation affecting liver, pancreas, kidneys, heart, skin, and various lymph nodes. Mycobacteria were isolated from pulmonary lymph node and liver, identified as <em>Mycobacterium (M.) xenopi</em> a non-tuberculous mycobacterial species of human relevance especially in cases of underlying immunodeficiency. Subsequent characterization using ITS-sequencing and MLST-pattern analysis revealed that the isolate was identical with a Canadian strain of human origin indicating a high degree of conservation across countries and host species. This case represents to our knowledge the first report of a clinical <em>M.&nbsp;xenopi</em> infection in a host species not yet reported.</p>
  a1439-0299