02383nas a2200277   4500000000100000000000100001008004100002260007000043653002300113653001500136653002500151653001700176653001200193653001100205100001300216700001700229700001700246700001200263700001200275245014200287250000800429300001200437490000700449520163500456022001402091       2015                            d  c07/2015bSchlütersche Verlagsgesellschaft mbH & Co. KGaHannover10aDigital dermatitis10aMortellaro10asalicylic acid paste10atetracycline10awashing10acattle1 aJ Kofler1 aC Innerebner1 aR Pesenhofer1 aA Hangl1 aA Tichy00aEffectiveness of salicylic acid paste for treatment of digital dermatitis in dairy cows compared with tetracycline spray and hydrotherapy  a7/8  a326-3340 v013 aThe effectiveness of salicylic acid paste (PASTE) was tested for topical treatment of 25 acute and 25 chronic digital dermatitis (DD) lesions. Control groups with the same number of acute and chronic DD lesions were treated with topical oxytetracycline spray (SPRAY) and by washing only with water (HYDRO) respectively. The therapeutic effects were evaluated using a pain score, the healing rate, the lesion size and other parameters. Pre-treatment and control examinations were carried out on day 0, 4, 14 and 21. In the PASTE group, 72.0% of acute DD lesions were pain free and 24.0% of acute DD lesions were healed on day 21 showing a normal skin surface (M0). Only 28.0% of acute DD lesions treated with SPRAY and 12.0% treated with HYDRO had healed on day 21. A significantly higher healing rate was revealed in acute lesions for the PASTE compared to the HYDRO group (p  lt; 0.05) for all three re-checks, and for the PASTE group compared with the SPRAY group (p  lt; 0.05) for day 4 and day 14. Healing rates of chronic DD lesions were higher in the PASTE group with 44.0% on day 14 and 2.0% on day 21, compared with 12.0% in the SPRAY and 2.0% in the HYDRO group on day 14, and 20.0% (SPRAY) and 28.0% (HYDRO) on day 21 respectively. The recurrence rate of lesions after they had healed during the study period was 14.5% in total. Digital dermatitis lesions treated with salicylic acid paste and a wrap showed significantly higher healing rates within the study period, odds ratios for healing of acute lesions with PASTE were 4.5 to 2.7 times higher than with SPRAY, and  9. to 2.4 higher compared with HYDRO.  a0005-9366