01921nas a2200277   4500000000100000000000100001008004100002260007000043653001100113653002000124653001200144653002600156100001400182700001200196700001100208700001200219700002000231700001900251700001500270245013800285250000800423300001200431490000800443520117800451022001401629       2016                            d  c05/2016bSchlütersche Verlagsgesellschaft mbH & Co. KGaHannover10arodent10amycobacteriosis10aGiardia10aformalin inactivation1 aY Barthel1 aS Drews1 aM Fehr1 aM Moser1 aK Mätz-Rensing1 aW Baumgärtner1 aP Wohlsein00aConcurrent infection with Mycobacterium avium subsp. hominissuis and Giardia duodenalis in a chinchilla (Chinchilla lanigera f. dom.)  a5/6  a242-2460 v1293 aA 3-year-old, female chinchilla (Chinchilla lanigera f. dom.) suffered from prolonged vaginal discharge. Sonographically, multiple nodules were detected in the uterus, and the lung showed a diffuse radiodensity. Ovario-hysterectomy was performed and histology of the uterus revealed a severe multifocal pyo-granulomatous metritis with myriads of acid-fast rod-shaped bacilli. Microbiological culture of formalin-fixed uterine tissue and a native vaginal swab resulted in the growth of mycobacteria that were identified as Mycobacterium (M.) avium subsp. hominissuis. The animal was euthanized and pathomorphological examination revealed severe multifocal granulomatous inflammation of lung, mediastinal and mesenteric lymph nodes, intestine, pancreas and kidneys. In addition, an infection of the small intestine with Giardia duodenalis was confirmed immunohistochemically. This is the first report describing a concurrent infection with M. avium subsp. hominissuis and Giardia duodenalis in a chinchilla. Both pathogens represent a potential health risk especially for young or immunosuppressed persons, in particular if infected animals show unspecific clinical symptoms.  a0005-9366