01577nas a2200241   4500000000100000000000100001008004100002260007000043653001900113653001600132653000800148653002200156100001200178700001700190700001500207700001200222700001300234700001200247245014800259490000800407520090600415022001401321       2019                            d  c12/2019bSchlütersche Verlagsgesellschaft mbH & Co. KGaHannover10agut microbiota10apathobionts10aSPF10ahealth monitoring1 aL Benga1 aE Engelhardt1 aC Gougoula1 aI Knorr1 aW Benten1 aM Sager00aBehind the SPF concept – In house distribution of selected bacteria with potential impact on experimental models among the laboratory rodents0 v1323 aParticular bacterial species belonging to gut microbiota have impact on certain animal models. Currently, the distribution of such microbes among the experimental rodents is largely unknown. The goal of the present investigation was to survey the prevalence of selected bacteria with possible effects on research, such as Helicobacter spp., segmented filamentous bacteria (SFB), Bacteroides fragilis and Akkermannsia muciniphila, among the laboratory mice and rats of an experimental facility. Overall the distribution and the prevalence of the bacteria tested varied among the microbiological units tested from very few to nearly 100% positive samples. Their distribution into the experimental rodents seems to be unpredictable and preliminary tests for such agents or better for their presence in the context of whole gut microbiota is indicated in order to warrant the success of particular models.  a0005-9366