01825nas a2200241 4500000000100000000000100001008004100002260007000043653002300113653003300136653002200169653003700191653001000228100001300238700001300251700001500264700001500279245018300294300001200477490000800489520107200497022001401569 2011 d c05/2011bSchlütersche Verlagsgesellschaft mbH & Co. KGaHannover10aavian polyomavirus10abudgerigar fledgling disease10afeather dysplasia10askin pathology of viral diseases10abirds1 aV Herder1 aA König1 aF Seehusen1 aP Wohlsein00aAvian polyomavirus infection of a fledgling budgerigar (Melopsittacus undulatus) and differential diagnoses of viral inclusions in psittacine birds – case report and mini-review a209-2160 v1243 aA two-week-old budgerigar (Melopsittacus undulatus) of an outdoor aviary diedsuddenly and was submitted for determination the cause of illness and death.Macroscopically, the sparsely feathered animal was in a poor body condition.Histopathological examination revealed in various mesenchymal and epithelialtissues, numerous up to 15 amp;#956;m in diameter large intranuclear, amphophilic tobasophilic inclusion bodies with a clearing of the centre. Additionally, a featherdysplasia and retention hyperkeratosis of feather follicles was found. Ultrastructurally,viral particles of approximately 35 nm in diameter were detected in thefeather follicle epithelium. A PCR for Avian Polyomavirus on fresh skin sampleswas negative whereas on formalin-fixed kidney samples with a high amount ofviral inclusion bodies yielded a positive result. In addition, viral inclusion bodydiseases, like Avian Poxvirus, Psittacine Beak and Feather disease virus, AvianAdenovirus, Psittacine Herpesvirus and papillomavirus of psittacines are summarizedand compared in the present article. a0005-9366