01595nas a2200181   4500000000100000000000100001008004100002260007000043653001300113653002800126653001300154100001300167700001800180245007600198490000800274520111700282022001401399       2017                            d  c01/2017bSchlütersche Verlagsgesellschaft mbH & Co. KGaHannover10aserology10atube agglutination test10adog sera1 aW Herbst1 aJ Langenstein00aA survey for antibodies to Brucella canis in dog sera from 2004 to 20130 v1303 aBrucella (B.) canis is a zoonotic pathogen that is mainly associated with reproductive tract disorders in dogs. It has been reported from almost all parts of the world. As actual epidemiological studies are very scarce in Germany the purpose of the present study was to estimate the current spread of this infection. A total of 4724 dog sera from years 2004–2013 were tested for antibodies to B. canis by the tube agglutination test. Titers ranging from 50 to 1600 were detected in 284 (6.0%) dogs. In the majority of cases (83.7% of agglutinating sera) low titers, 50 and 100, respectively, were achieved. In contrast, less than 1% of sera (n = 46) had titers of ≥ 200 only. Twenty-eight of these sera (0.6% of all sera) showed a titer of 200, ten (0.2%) a titer of 400, six (0.1%) of 800 and two sera (0.04%) yielded a titer of 1600 each. Assuming that titers of ≥ 200 are positive a sero-prevalence of 0.94% was achieved. This result was only a little below that of year 1978 (Weber and Schliesser, 1978) indicating a very slow spread of B. canis infection in dogs and confirming its sporadic character.  a0005-9366