@article{4697, keywords = {mesothelioma, visayan spotted deer, serosa, Tumor, immunohistochemistry}, author = {M Bazin and J Schwinn and B Kühl and F Armando and A Beineke}, title = {Malignant epithelioid mesothelioma in a Visayan spotted deer (Cervus alfredi)}, abstract = {

A Visayan spotted deer with progressive weight loss showed diffuse thickening and nodular changes of the pleura and peritoneum. Histology revealed a highly pleomorphic, predominantly solid neoplasm, consistent with a malignant epithelioid mesothelioma. By immunohistochemistry, expression of pan-cytokeratin, cytokeratin 5/6, and vimentin was found in tumor cells. In addition, scattered expression of calretinin, desmin and α-smooth muscle actin was present within the neoplasm. Mesotheliomas should be considered as a potential differential diagnosis for proliferative processes involving the serosa in cervids.

}, year = {2022}, journal = {Berliner und Münchener Tierärztliche Wochenschrift}, volume = {135}, pages = {1–6}, month = {02/2022}, publisher = {Schlütersche Fachmedien GmbH}, address = {Hannover}, issn = {1439-0299}, doi = {10.2376/1439-0299-2021-28}, language = {English}, }