@article{4105,
  keywords = {Thoroughbred, XY testicular DSD, horse racing sport},
  author = {C Dierks and H Sieme and M Piechotta and S Lehner and J Merkt and H Uphaus and E Klug and O Distl},
  title = {Elevated testosterone levels in a racing horse due to an XY testicular disorder of sexual development},
  abstract = {A female thoroughbred successful in horse racing was positively tested for high testosterone values. This horse neither showed stallion-like-behaviour nor signs of ambiguous external genitalia. The karyotype of this horse was 2n=64,XY and the sex-determining region of Y (SRY) PCR was positive. Hair samples tested for naturally testosterone revealed values normal for stallions, and tests for eight synthetic testosterone esters remained negative. The phenotype, ultrasonographic examination, hormone status, cytogenetic evaluation and molecular diagnostics lead to the diagnosis of an XY testicular disorder of sexual development (DSD) due to a complete androgen insensitivity syndrome. To our knowledge this is the first report about a thoroughbred in racing sports with an XY testicular disorder of sexual development. To date, intersex racing horses have never been described in thoroughbreds or a regulation for intersexes in regard to horse races has been issued. },
  year = {2015},
  journal = {Berliner und Münchener Tierärztliche Wochenschrift},
  volume = {128},
  edition = {7/8},
  pages = {335-339},
  month = {07/2015},
  publisher = {Schlütersche Verlagsgesellschaft mbH & Co. KG},
  address = {Hannover},
  issn = {0005-9366},
  doi = {10.2376/0005-9366-128-335},
  language = {English},
}