@article{3683,
  author = {G Krammer and J Aurich},
  title = {Concentrations of ß-carotene (Carofertin®)and vitamin A in plasma of pigs after intramuscular injection of ß-carotene},
  abstract = {Limited information is available about the absorption and distribution of parenterally administered  amp;#946;-carotene in pigs. Therefore plasma concentrations and pharmacokinetic parameters of  amp;#946;-carotene, its influence on plasma vitamin A concentration as well as the safety and tolerability of an intramuscularly administered  amp;#946;-carotene preparation (Carofertin®) were analysed. Five gilts were injected with a single dose of 70 mg  amp;#946;-carotene in an injectable aqueous solution. The mean pre-treatment plasma  amp;#946;-carotene concentration was below 10  amp;#956;g/ml. After injection, plasma  amp;#946;-carotene values increased rapidly and reached a peak of 13.8 ± 5.4  amp;#956;g/ml after 24 hours. For a duration of 72 hours, plasma  amp;#946;-carotene concentrations were significantly increased compared to baseline values (p},
  year = {2008},
  journal = {Berliner und Münchener Tierärztliche Wochenschrift},
  volume = {115},
  pages = {444-448},
  month = {12/2008},
  publisher = {M. & H. Schaper GmbH},
  address = {Hannover},
  issn = {0341-6593},
  doi = {10.2376/0341-6593-115-444},
  language = {English},
}