@article{2513,
  author = {C Müller and H Hamann and R Brahm and H Grußendorf and C Rosenhagen and O Distl},
  title = {Analysis of systematic and genetic effects on the prevalence of different types of primary lens opacifications in the wildboar-colored wirehaired Dachshund},
  abstract = {The aims of this study were to analyze the influence of systematic environmentaleffects on the prevalence of primary non-congenital cataract (CAT), fibreglasscataract in the nucleus (FCN), and prominent suture lines (PSL) and to estimatethe heritabilities of these eye diseases in the wild-boar-colored wirehairedDachshunds (WWD) bred in the German Dachshund Club 1888 e.V. (DTK). Dataincluded 2,430 WWD born between 1995 and 2003 that were examined between1996 and 2005 by veterinary ophthalmologists. CAT was diagnosed in 3.83 % ofthe 2,430 dogs, FCN in 3.74 %, and PSL in 2.76 %. Sex, size, inbreeding coefficient,the age of the dog at examination, experience of the veterinary ophthalmologistand the additive genetic effect of the animal were considered in the multivariatelinear model. The age of the dog at examination had a significant influence onthe prevalence of FCN. The degree of experience of the veterinary ophthalmologistsignificantly influenced the prevalence of FCN and PSL. Using a transformationinto the Dempster-Lerner threshold model, heritability estimates (hDL2) forWWD were hDL2 = 0.39 ± 0.13 for CAT, hDL2 = 0.36 ± 0.11 for FCN andhDL2 = 0.49 ± 0.12 for PSL. Positive genetic correlations (rg) were found betweenCAT and FCN (rg = 0.58 ± 0.21), between PSL and FCN (rg = 0.83 ± 0.23), andbetween CAT and PSL (rg = 0.79 ± 0.06). The eye diseases investigated here in theDachshund were found to be genetically influenced and positively correlatedtraits.},
  year = {2008},
  journal = {Berliner und Münchener Tierärztliche Wochenschrift},
  volume = {121},
  pages = {286-291},
  month = {07/2008},
  publisher = {Schlütersche Verlagsgesellschaft mbH & Co. KG},
  address = {Hannover},
  issn = {0005-9366},
  doi = {10.2376/0005-9366-121-286},
  language = {English},
}