@article{2476,
  author = {H Müller and R Johne},
  title = {Rotaviruses: diversity and zoonotic Potential - a brief review},
  abstract = {Rotaviruses, a genus within the family Reoviridae, are among the most important etiological agents of severe diarrhoeal illness in humans and animals worldwide. Their genome, consisting of 11 Segments of double-stranded RNA, is charac-terized by genetic variability including (i) point mutations, (ii) genomic reassort-ment, and (iii) genome rearrangements,thus leading to the considerable diversity of rotaviruses. Animal rotaviruses are regarded as a potential reservoirfor genetic exchange with human rotaviruses.There is now increasing evidence that anima rotaviruses can infect humans, either by direct transmission of the virus or by contributing one or several genes to reassortants with essentially a human strain genetic background. As mixed infections are a prereguisite for reassortment events, cosurveillance of animal and human rotavirus strains will be vital to gain a better understanding of the relationships between cocirculating viruses, as well as assessing any relevant vaccination programs.},
  year = {2007},
  journal = {Berliner und Münchener Tierärztliche Wochenschrift},
  volume = {120},
  pages = {108-112},
  month = {03/2007},
  publisher = {Schlütersche Verlagsgesellschaft mbH & Co. KG},
  address = {Hannover},
  issn = {0005-9366},
  doi = {10.2376/0005-9366-120-108},
  language = {English},
}