@article{1834,
  keywords = {Ixodes ricinus},
  author = {C Klaus and B Hoffmann and U Moog and U Schau and M Beer and J Süss},
  title = {Can goats be used as sentinels for Tick-borne encephalitis (TBE) in nonendemic areas? Experimental studies and epizootiological observations},
  abstract = {A goat flock grazing year-round on a meadow in a  #147;TBE non-risk area #148; in Thuringia, Germany, with a history of only isolated human TBE cases was examined repeatedly for TBE virus-(TBEV)-specific antibodies and TBEV RNA between October 2008 and December 2009. Surprisingly, TBEV specific antibodies were detected in one goat, which had never left this area. To compare the results of a natural contact to TBEV with a defined contact to TBEV, two goats were immunized experimentally. Both animals developed TBEV-specific antibodies, one goat however in a delayed and reduced manner. In addition, 177 ticks were collected from the meadow in May and June 2009, and were examined by real-time RT-PCR. However, no TBEV RNA could be detected. The results suggest that goats can be used as TBEV sentinels in defined areas. To verify this observation further investigations with a large number of animals are recommended.},
  year = {2010},
  journal = {Berliner und Münchener Tierärztliche Wochenschrift},
  volume = {123},
  pages = {441-445},
  month = {10/2010},
  publisher = {Schlütersche Verlagsgesellschaft mbH & Co. KG},
  address = {Hannover},
  issn = {0005-9366},
  doi = {10.2376/0005-9366-123-441},
  language = {English},
}