@article{1405,
  keywords = {3R principle, refinement, animal welfare , severity classification},
  author = {L Keubler and R Tolba and A Bleich and C Häger},
  title = {Severity assessment in laboratory animals: a short overview on potentially applicable parameters},
  abstract = {A key element of the 3R´s refinement principle as developed by Russel and Burch  is an evidence based severity assessment in laboratory animals. In this context, the grading of pain, suffering and distress experienced by laboratory animals has recently become central in national and European legislation. However, apart from the magnitude of potentially utilizable techniques the actual availability of scientifically sound, adequate and applicable scales is scarce. This demands a combined effort to identify and define objective, classifiable and standardized parameters to assess severity in experimental conditions, providing a basis for animal welfare based recommendations. Here, a short overview is given on classical and upcoming parameters of severity assessment in animal based research.},
  year = {2018},
  journal = {Berliner und Münchener Tierärztliche Wochenschrift},
  volume = {131},
  month = {07/2018},
  publisher = {Schlütersche Verlagsgesellschaft mbH & Co. KG},
  address = {Hannover},
  issn = {0005-9366},
  doi = {10.2376/0005-9366-17105},
  language = {English},
}